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Many potential nanocarriers were investigated for intrathecal administration: for example, alginate/chitosan composite and maltosyl beta-cyclodextrin for improved delivery efficiency of bupivacaine [97, 98]
Glucagon-like peptide-1 (GLP-1) receptor agonists, FDA-approved medications for type 2 diabetes and obesity, are increasingly recognized for potential anti-inflammatory properties beyond their metabolic effects
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Stop and review with a clinician if blood sugar climbs significantly, if IGF-1 rises far above normal, or if side effects do not settle
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