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The upper arm may require help The back or outer upper arm is also an approved GLP1 injection area, but it can be harder to use alone

January 2026 milestone: The FDA approved an oral formulation of Wegovy (semaglutide) for chronic weight management in December 2025 the first GLP-1 pill ever approved for obesity treatment

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The effects typically peak during dose escalation phases and improve substantially once patients reach stable maintenance doses

Nucl Recept Signal 7(1):e003 Polyzos SA, Frhbeck G, Kiortsis DN (2023) Peptide polyagonists for the treatment of nonalcoholic fatty liver disease