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Conventional randomized controlled trials, long regarded as the gold standard, often fail to accommodate the biological heterogeneity, comorbidities, and evolving pathophysiological trajectories that characterize chronic brain diseases
Side effects are typically mild, temporary, and manageable
Several NADs have entered the clinical trial recently, and some have been approved for therapeutic use in different fields
Some GI adjustment (mild nausea, fullness) is normal and passes within 2-4 weeks
Exactly what is it
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