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Common signs and symptoms include the following: Cognitive issues, especially those that deal with memory Extreme fatigue Depression Frequent headaches Problems with maintaining balance Changes in vision Megaloblastic anemia Heart palpitations Pale skin Weight loss Infertility Numbness and tingling in the hands and feet A sore tongue Low appetite Constipation Vitamin B12 Deficiency Risk Factors You have a higher risk of developing vitamin B12 deficiency if you have specific health problems
As discussed in gut health research more broadly, microbiome disruption drives: Intestinal permeability Systemic inflammation Impaired neurotransmitter production Immune dysregulation In the context of long COVID, gut dysfunction may represent both a consequence of the initial infection and an ongoing driver of systemic inflammatory and neurological symptoms
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