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Clinical trials (such as the STEP trials) utilized once-weekly dosing because that rhythm allows the drug to build to a stable Steady State over 4 to 5 weeks
How the Right Foods Can Help What you eat while taking tirzepatide can make a big difference in how you feel each day and how much weight you are able to lose
R.PayneJ
The SURMOUNT-5 trial showed that maximum-dose tirzepatide produces about 47% more weight loss than maximum-dose semaglutide, so they are clearly not equivalent at their respective maximums
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