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Educational background: Semaglutide as a molecule was originally developed for type 2 diabetes by Novo Nordisk and is sold under the brand names Ozempic (for diabetes) and Wegovy (for chronic weight management, introduced for weight management in 2021)

The prognosis varies depending on the underlying cause of the deficiency and how severe the deficiency is

doi: 10.1111/apt.15033 196 SahooDKHeilmannRMPaitalBPatelAYadavVKWongDet al

Obesity 33(3):452462 Lincoff AM, Brown-Frandsen K, Colhoun HM, Deanfield J, Emerson SS, Esbjerg S et al (2023) Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes

The FDA approves high-dose Liraglutide and Semaglutide for obesity management and allows their use for overweight patients with comorbidities (21)