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It is instantly sensed by the congested open market that runs along the street in front of the row of dark run-down flatsshacks haphazardly perched on top of one another giving the impression that at any moment the entire blighted complex will collapse under its own weight, leaving nothing but rubble where elevated rubble had stood

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This is mechanistically demonstrated in breast cancer models, where SFN, by activating the Nrf2 pathway, reduces the secretion of prostaglandin E2 (PGE2) from tumor cells, thereby triggering MDSCs to switch from an immunosuppressive to an immunogenic phenotype and inhibiting their expansion (76)

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