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Bacteria and fragments of bacteria are able to slip past the gut wall and drain into the liver
A meta-analysis of 27,729 participants found the overall rate of GI side effects to be 11.66%
These are considered to be serious health conditions that increase the risk for premature death, heart attack, stroke and other health issues (FDA News Release March 8, 2024)
Most side effects during the first few weeks are gastrointestinal: nausea, constipation, reduced appetite, and occasionally diarrhea
Three different rodent diets (Table 1) were provided ad libitum to 20 animals each (Research Diets, Inc., New Brunswick, USA)
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