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Sakamuru S, Attene-Ramos MS, Xia M
Theoretical risks Long-term or high-frequency use raises theoretical concerns about copper accumulation
Plateaus are common and do not automatically mean treatment has failed
Theres no universally best time, but most users inject: Once daily in the morning , or Split into two doses : AM and PM for more stable coverage (especially for injury or gut repair) For injury-specific cases, timing the dose post-workout or before sleep may support natural repair cycles
Blood, 2008
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