People using insulin or medicines that stimulate insulin release may require additional blood-glucose monitoring
Quick Answer: GLP-1 medications typically show initial effects on blood glucose within 1-2 weeks and appetite suppression within days to weeks, but reaching full therapeutic response requires 12-20 weeks as doses gradually increase
GLP-1 drugs have obviously been all the rage for weight loss, and there has been some off-label use of them to treat liver disease like MASH, but in the Phase III ESSENCE trial, after 72 weeks, 63% of patients on Wegovy saw their steatohepatitis resolved without any worsening of fibrosis, compared to just 34% with placebo
Because Rybelsus is taken as a tablet, patients often ask about the role of oral semaglutide compared with injections
What specific risks must be emphasized when counseling high-risk patients about GLP-1 therapy, and how do you document this patient education/ informed consent