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In one study [16], AdIGF-1-infected MSCs were fixed in fibrin glue and implanted in rat cartilage defects, which led to satisfactory cartilage repair (type II collagen matrix secretion and hyaline cartilage production)
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2012;4:a011254
While the former was primarily managed with insulin or metformin to control glucose levels, the latter was often treated with lifestyle interventions or less effective pharmacotherapy
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