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The combination of direct weight loss and the anti-inflammatory GLP-1 mechanism (which we cover in our guide to GLP-1 agonists and joint pain) may produce benefits in joint disease that go beyond what weight loss alone would achieve
In pooled placebo-controlled trials, acute gallbladder disease was reported by 0.6% of Mounjaro-treated patients
If you notice permanent pattern changes (frontal recession, crown thinning), see a dermatologist to evaluate whether you have underlying androgenetic alopecia that needs different treatment
Most patients benefit from finding the lowest effective long-term dose
6 Yet in 2016, data from the SUSTAIN-6 trial comparing semaglutide to placebo over two years showed a possible increased risk of complications of diabetic retinopathy, including vitreous hemorrhage
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