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doi:10.1136/bmjopen-2024-089477 Jensterle M, Rizzo M, Haluzk M, Jane A

However, further studies are needed to understand its role in renal hemodynamics, oxidative stress, fibrosis and cell damage, as weight loss could be only partially responsible for its pleiotropic benefits

Both native GLP-1 and GLP-1RA exert multiple actions in the cardiovascular system, including reduction of blood pressure in hypertensive individuals, inhibition of postprandial chylomicron secretion, attenuation of inflammation in the heart and blood vessels, and reduction of ischaemic cardiac injury, but also increases in heart rate (Fig

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Adequate fluid intake helps keep stools soft and supports the action of both dietary fibre and osmotic laxatives