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Note that drug costs are reported net of rebates received by plans

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WARNING Before using topiramate, tell your health care provider about your medical history, especially if you have: narrow angle glaucoma and nearsightedness kidney problems, such as kidney stones liver problems depression or thoughts of suicide lung or breathing problems metabolic acidosis high blood ammonia levels long-term diarrhea low body temperature a diet high in fat and low in carbohydrates, aka a ketogenic diet brittle bones Topiramate may cause some people to sweat less

The FDA has recognized these cardiovascular benefits through multiple approvals

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