Key takeaways Certain dietary supplements like protein powder, calcium, and fiber may enhance GLP-1 secretion, which plays a role in insulin production and appetite regulation
Efficacy and safety of dulaglutide added onto pioglitazone and metformin versus exenatide in type 2 diabetes in a randomized controlled trial (AWARD-1)
The dose is then increased in 2.5 mg increments every 4 weeks as tolerated, with typical maintenance doses ranging from 5 mg to 15 mg
However, translating these findings into disease-modifying therapies requires standardization, the identification of robust biomarkers (e.g., SCFAs, LPS/LBP, bile acids, cytokine profiles), and the development of tailored clinical strategies based on disease stage and distinct microbiome-based patient subgroups
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