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Autoimmune diseases, such as lupus and rheumatoid arthritis, stem from an overactive immune system that attacks your bodys tissues

Semba RD, Nicklett EJ, Ferrucci L

Apart from external inducers, endogenous triggers such as mast cell-derived histamine, proteases and eicosanoids can increase intestinal permeability, either directly or via stimulation of neurons of the enteric nervous system [194],[199],[200]

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