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The drugs are expensive, and experts say the recent spike in popularity has already led to shortages and increased hesitancy among insurance providers to cover these drugs

This matters because PCOS-related skin issues are usually driven by internal stress , not skincare failure

Adjusting Sermorelin Dosage: Monitoring and Side Effects Recognizing Signs of Underdosing or Overdosing Underdosing signs Persistent low energy and poor sleep quality Minimal change in body composition IGF-1 remains below age-adjusted normal Overdosing signs Joint or muscle aches Fluid retention and mild swelling Numbness or tingling in hands (carpal tunnel symptoms) Common Side Effects and How to Mitigate Them Injection-site redness or itching: apply a cold compress

Because all prescribing is supervised within a bariatric medical practice, any concerns can be addressed quickly and medication plans adjusted when necessary

Atherosclerosis 237 , 369373 (2014)