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Open communication between patients and healthcare teams is essential for optimising both safety and therapeutic outcomes

IgG can induce pain independent of overt inflammation or nerve damage, and a role for antibodies has been identified in other nociplastic pain conditions like complex regional pain syndrome

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If taking higher doses, it is highly recommended to split the administration (e.g., one dose in the morning and one in the early afternoon) to maintain steady blood levels of the active compounds throughout the day

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