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Prostaglandins promote narrowing of the blood vessels in the uterus, instigate uterine contractions, reduce blood flow to the uterus and increase the sensitivity of nerves in the uterus
Local injection site reactions were uncommon in the Phase 2 trial, occurring at a lower frequency than systemic gastrointestinal events
While this strategy has shown promise in animal models, its clinical effectiveness remains controversial
Chu L, Xi Z, Ma R, et al
Do not use on cuts wounds or other open areas of skin
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