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Published June 14, 2021
Patients who stop at this point typically retain results for 4 to 8 months before drifting back to their untreated trajectory
Cryo-EM movies were collected on a Titan Krios electron microscope (Thermo Fisher Scientific) operated at an accelerating voltage of 300 kV
High stress levels increase cortisol, which can slow weight loss and increase emotional eating
In the pancreas, these agents enhance glucose-dependent insulin secretion while suppressing inappropriate glucagon release, improving glycemic control with a low risk of hypoglycemia when used alone (though this risk increases when combined with insulin or sulfonylureas)
![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
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