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Dehydroepiandrosterone (DHEA) may inhibit mitophagy via suppression of AMPK/SIRT1 pathway (Ma et al., 2024)

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Dysregulated IL-6 signaling contributes to pathogenic inflammation in autoimmune diseases such as rheumatoid arthritis and idiopathic juvenile arthritis 57 and anti-IL-6R therapies such as tocilizumab are successfully used in autoimmune disease 58

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