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Abbreviations: HbA1c

2) Joint Pain and Cartilage Damage: Arthritis (Osteoarthritis and Rheumatoid Arthritis): While direct human studies on arthritis are limited, BPC-157s ability to promote collagen production and reduce inflammation suggests potential benefits for managing arthritis symptoms (8, 9)

The proposed chain of effects looks like this: NNMT inhibited nicotinamide is no longer inactivated by methylation and becomes available for conversion to NAD+

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doi: 10.1016/j.isci.2024.109219 105 TadokoroTIkedaMIdeTDeguchiHIkedaSOkabeKet al