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MizumaT.2009Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: a study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10.3781-2, (August 2009),140141,0378-5173 81

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Although the results indicated an increment in the expression levels of Star, Cyp11a1 , and Hsd17b3 in the MSG + LC 100 group compared to the MSG group, the differences were not statistically significant

Many topical serums absorb into the upper epidermis without ever reaching the papillary dermis where fibroblasts live