tirzepatide effect Tirzepatide) is the most effective obesity drug we have to date, and it seems to be thanks to its “dual effect”: it acts as a GLP-1 receptor agonist but also as another Tirzepatide: How Does It Work

Semaglutide is currently the most prominent approved option in this class: Ozempic (semaglutide injection) licensed for type 2 diabetes management Wegovy (semaglutide 2.4 mg injection) licensed specifically for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity

This triple agonism distinguishes retatrutide from existing approved agents such as semaglutide (a GLP-1 receptor agonist) and tirzepatide (a dual GIP/GLP-1 agonist)

JAMA 332 , 952953 (2024)

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