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The SURMOUNT-1 trial showed average weight loss of 20.9% at the 15 mg dose, with 57% of participants losing more than 20% of body weight
This is why slow titration produces fewer side effects at the same final dose
PMID: 10496658.
Plasmids of wildtype and mutants of ARE motifs were transfected to K562 (#CRL-3344, ATCC), an erythroleukemia cell, along with pDsRed1-N1 (PT3405, Clontech), which is used as a transfection efficacy control
Rheumatology (Oxford) 64, 3085-3089 (2025)
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