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doi: 10.2147/CLEP 423 LattieEGAntoniMHFletcherMAPenedoFCzajaSLopezCet al
Insights into the inhibitory mechanisms of NADH on the heterodimer of human NAD-dependent isocitrate dehydrogenase
It activates the innate repair receptor (IRR) a heterodimeric receptor (EPOR/CD131) selectively upregulated in injured tissue to produce anti-apoptotic, anti-inflammatory, and nerve-regenerative effects without stimulating red blood cell production or carrying EPOs cardiovascular risks
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