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however, its exact contribution to brain Se transport was not systematically studied and it seems to be rather limited since megalin / mice do not exhibit neurological phenotype associated with Se deficiency (Kurokawa et al., 2014b), typical for Selenop / or Lrp8 / mice
The underlying mechanisms involve critical biochemical processes such as DNA synthesis, methylation reactions, neurotransmitter production, and myelin synthesis, all of which are essential for the proper functioning and maintenance of the nervous system
Proteins are fragile
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