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The deposition of acylcarnitine also disrupts the function of the Na + -K + -ATP pump and affects the action potentials, polarization, hyperpolarization, and depolarization cycles of the myocardial cell membrane, which further affects the electrophysiological stability of the heart [295]
Later, a regression model was created in a study of MTHFR C677T genotype and DNA methylation in schizophrenia subjects, which found females with TT genotype were associated with the lowest global methylation 43
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