doi: 10.1111/dom.12674 27 AhrnBHirschIBPieberTRMathieuCGmez-PeraltaFHansenTKet al
These powerful medications can help reshape metabolic health, but they can also leave you backedup, bloated, and uncomfortable
The mechanism is still unclear, but one oft-cited study of women who were overweight or obese and also had prediabetes found that NAD supplementation with nicotinamide mononucleotide (NM), an NAD precursor, for 10 weeks improved insulin sensitivity
Most protocols divide administration into loading and maintenance phases
Before committing to combination therapy, it is worth stepping back and asking a blunt question: does adding phentermine to tirzepatide actually provide enough additional benefit to justify the added risk, monitoring burden, and cost