A significant contributing factor to the prevalence of T2DM is obesity, which is strongly associated with serious consequences such as chronic kidney disease, hypertension, stroke, and liver disease that impair both the quality and quantity of life as life expectancy declines with rising body mass index (BMI) [2]

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However, preclinical studies demonstrate therapeutic effects with once-daily or even less frequent administration, suggesting tissue distribution, receptor binding, or cellular signaling effects extend beyond plasma clearance
Good hygiene can help reduce this risk