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GHK-Cu supports the production of proteins and lipids that reinforce the barrier, reduce transepidermal water loss (TEWL), and promote smoother, more hydrated skin

GHK itself has been identified in human biological contexts, but the evidence for GHK-Cu depends heavily on route, formulation, and study design

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When applied to the skin, it may also cause mild skin or eye irritation ( Additionally, there is concern over mixing MSM with alcohol since other sulfur-containing medications can cause adverse reactions when mixed with alcoholic beverages ( However, no studies have explored this potentially problematic combination yet