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[42] However, one should note that glutathione mainly affects the melanin indices and ultraviolet spots in the sun-exposed areas

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238,242 Isocitrate dehydrogenase 3 (IDH3), a pivotal rate-limiting enzyme in the TCA cycle, is downregulated, leading to oxidative phosphorylation uncoupling and lactate accumulation in the brains of AD patients and AD transgenic mice

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