Bao Y, Xu Z, Cheng K, Li X, Chen F, Yuan D, Zhang F, Che AR, Zeng X, Zhao YD, Xia J
Kathleen Grant, Ph.D., Senior Scientist, Oregon National Primate Research Center
This delicate balance is an interplay between ROS production and the up-regulation of the AOX pathways CAT and GSH which opposes the apoptotic process (124)
designed the expression constructs, purified the receptor complexes, screened specimen, prepared the final samples for negative staining/data collection towards the structure and participated in manuscript preparation
While the specific mechanism causing the effects on the gastrointestinal tract are not fully elucidated, studies suggest GLP-1 and its analogues likely exert effects on the vagus nerve and inhibit cholinergic neurotransmission in the gastrointestinal system to prevent movement of the intestine