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Mice expressing OSKM had significantly higher levels of serum B 12 than WT mice following the bolus (Extended Data Fig

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its administered via injections or capsules in clinical settings.[4] It enhances fat burning, energy, insulin sensitivity, muscle preservation, and repair, while indirectly boosting NAD+ by slowing depletion.[5][23][24] Its membrane-permeable nature allows efficient cellular entry, making it suitable for therapeutic use