A 2007 double-blind, multicenter trial (n=102) showed ALC 1,500 mg/day significantly improved tender point count, total myalgic score, depression, and musculoskeletal pain compared to placebo.[9] A 2015 RCT found ALC 1,500 mg/day comparable to duloxetine 60 mg/day for pain and depression.[8] Most notably, a 2023 RCT demonstrated that adding PEA 1,200 mg/day + ALC 2,000 mg/day to ongoing duloxetine + pregabalin therapy produced significantly greater improvements in Widespread Pain Index, FIQR, and FASmod scores.[7] Role in Treatment: ALC can be used as monotherapy or adjunctive therapy in fibromyalgia
In 2014, he conducted a 6-month clinical trial in which 54 participants were supplemented with 250 or 1000 mg/day of Setria Glutathione
CJC-1295 and Ipamorelin vs
Having it all administered as an injection (in the bum bum) forces the body to absorb a higher level of the vitamin at a faster pace, more than taking B12 tablets for a few weeks
Global regulation of nucleotide biosynthetic genes by c-Myc