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High-fat, Western-style diets, characterized by high saturated fats, refined sugars, and low fiber, have been associated with gut dysbiosis, increased neuroinflammation, and exacerbation of Alzheimers pathology, including A aggregation and tau hyperphosphorylation

In clinical trials, patients on semaglutide lost about 15% of their starting body weight on average over 68 weeks

By maintaining intestinal barrier integrity and inhibiting ileal inflammatory chemicals, kefir may prevent to mucosal leakage and systemic inflammation (133)

Because of the social stigma associated with obesity, mental health issues, including sadness, anxiety, and poor self-esteem are common

It is a directly relevant compound for MASLD pathway and liver fat metabolism research