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Mitochondria consume 90% of the oxygen used by the cell, and 12% of all electrons crossing through the respiratory chain end up becoming oxygen radicals (Raha et al., 2000), which induce cellular oxidation and immune suppression

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Although this study only featured the data from one person taking tirzepatide, it provides compelling data about how GLP-1 and GIP inhibitors alter electrical signals in the brain, said study co-first author Wonkyung Choi, a PhD candidate at the University of Pennsylvania School of Medicine in Philadelphia