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Increased oxidant-induced apoptosis in cultured nondividing human retinal pigment epithelial cells
Epigenetic and Cellular Reprogramming: By blocking NNMT-mediated methylation of nicotinamide, preserves NAD salvage pathway activity, increases SIRT-1 signaling, reduces histone deacetylation, and promotes metabolic reprogramming toward oxidative phosphorylation and glycolysis balance, supporting tissue repair and energy homeostasis 1-4
Tissue repair processes require water
Springer International Publishing, 123
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