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Even for the adapted herbivore species, these volatile compounds can cause direct physiological damage to herbivores due to their neurotoxic properties at high concentrations [101, 102]
In IBD, the expression levels of tight junction proteins such as ZO-1 and Occludin, is generally suppressed, leading to increased intestinal permeability, enhanced pathogen infiltration, and exacerbated inflammatory responses (Dong et al., 2022)
It is accepted that an excessive burden of ROS may lead to abnormal cell growth, corresponding changes in intracellular homeostasis and damage to important components of in the cell when the antioxidant defense and/or DNA repair mechanisms cannot balance the excess oxidants [29]
Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain
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