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These effects are usually short-lived and often lessen as the body becomes used to the medicine
Growing use of GLP-1 drugs highlights long-term weight challenges Currently, obesity affects over one billion people worldwide, who have higher odds of adverse outcomes like cardiometabolic disease
Individuals with insulin resistance, visceral adiposity, hypertension, and endothelial dysfunction exhibit early declines in cerebral blood flow and metabolic flexibility, long before overt dementia emerges
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