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Results showed that the ingredient significantly increased NAD+ levels in senescent fibroblasts, activated the SIRT1 signaling pathway, reduced the expression of senescence-associated -galactosidase (SA--gal), decreased intracellular reactive oxygen species accumulation, and promoted collagen synthesis
PMID: 34626851 Bendotti G, Montefusco L, Lunati ME, et al
This came to be known as the Myers' cocktail
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