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The scondary goal of the study was to compare the effects of combined treatment of cagrilintide and semaglutide versus treatment with cagrilintide alone and how the effected HbA1c levels and various parameters of glycemic control and bodyweight as well as the safety and tolerability of the treatment

In clinical trials, constipation rates with cagrilintide ranged from approximately 10% to 25% depending on the dose, compared to roughly 5% to 8% with placebo

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Prusiner, S

Alzheimers Disease International, pp