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These integrated analyses linked proteomic and metabolomic data to identify glutathione system dysregulation as a convergent mechanism in SAE

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A smaller quantity may lead to frequent reorders, while a larger quantity may not be suitable if the plan is still being adjusted

doi: 10.1038/labinvest.3780057 63 PatelVBBodigaSBasuRDasSKWangWWangZet al

Side effects are almost always worst during dose titration, when the medication is ramped up every 4 weeks