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History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy

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Nasal Sprays : Nasal B12 sprays have been shown to effectively raise B12 levels and offer a convenient, needle-free alternative for individuals who prefer non-injection options or have difficulty with traditional supplementation[23]

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