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GLP-1 exerts its effects through GLP-1R, a member of the class B G protein-coupled receptor family, mainly by activating the cAMP-protein kinase A (PKA) pathway to promote insulin release and improve insulin resistance (30,36)

During reactive microgliosis an increase of GSSG levels is observed

Angew Chem Int Ed 52(37):97239727 Malins LR, Cergol KM, Payne RJ (2013) Peptide ligation-desulfurization chemistry at arginine

These mechanisms are studied exclusively in experimental environments to better understand peptide-mediated signaling behavior at the molecular level and its influence on coordinated cellular responses associated with aging research

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