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Roche is advancing an oral GLP-1 receptor agonist, CT-996, which it gained through its 2024 acquisition of Carmot Therapeutics, a Berkeley, California-based bio/pharmaceutical company, in a deal worth up to $3.1 billion ($2.7 billion at closing plus $400 million in potential milestone payments)

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It is one of the most active areas of medical research globally

Namely, it is always applied alone (Sikiric et al., 1993