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These alterations result in a significantly extended half-lifeup to 120 times longer than native IGF-1due to reduced binding affinity to insulin-like growth factor-binding proteins (IGFBPs)
The sample must be collected in a yellow-top ACD tube and filled completely, since underfilled, clotted, or hemolyzed specimens are rejected
Diagnosis and management of mitochondrial disease: a consensus statement from the mitochondrial medicine society
doi: 10.1016/j.fct.2007.06.001 5 AkinmoladunA
A "yes" to all three does not guarantee safety, but a "no" to any of them is a disqualifying signal
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