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Mechanistically, we found that 4-OI inhibits GPX4-dependent lipid peroxidation by increasing the accumulation and activation of Nrf2

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Building on these findings, the investigation was quickly extended to drug-related rewards, and a growing body of preclinical studies across a range of substances suggests that GLP-1 receptor agonists can reduce behavioral patterns associated with addiction

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are questioning their role in addressing obesity, sparking debates about regulation and innovation