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Department of Health and Human Services, Food and Drug Administration, Pharmacy Compounding of Human Drug Products Under Section 503A of the Federal Food, Drug, and Cosmetic Act, June 2016, Revision 2

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You may be more likely to develop IC yourself if people in your family have the condition, even though no specific genetic factors causing IC have been proven

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They are produced by different types of cells and, once released in the body, induce specific reactions in adjacent cells (paracrine effect), in others far away (endocrine effect) or in those that have created them (autocrine effect)