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Stem Cells Transl Med (2021) 10(9):130419

Improved Skin Elasticity & Anti-Aging: Supports collagen production, improving skin tone, firmness, and reducing the appearance of wrinkles

At 2 weeks of age and 7 to 8 days after the induction of gene KO by Tam, the TamCar IGF-IR / mice show significant growth retardation with a body weight that was 70% of their control littermates, and demonstrate severely disorganized growth plates again, due to reduced cell proliferation and delayed differentiation, indicating comparable IGF-IR actions in growth plate development during embryonic and postnatal development (32)

Consistent daily supplementation at 500 mg for 8 to 12 weeks typically produces noticeable changes in skin tone

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